Reaction–diffusion basis of retroviral infectivity
نویسندگان
چکیده
منابع مشابه
A Study of Host Factors Influencing Retroviral Infectivity
While mammalian cells provide many of the molecules and machinery required by retroviruses to successfully achieve their replication cycle, they have also developed specific defences to protect themselves against viral infection. Existence of these antiviral "restriction" factors accounts for the limited ability of viruses to spread from one species to another. If a new virus becomes successful...
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Using adapted retroviruses for gene delivery is a modern and powerful tool in biological research as well as a promising approach for gene therapy. An important limitation for the extensive use of retroviral vectors is the low infection rate in target cells such as pulmonary vascular endothelial cells due to the insufficient infectivity of standard retrovirus supernatants that can only be overc...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
سال: 2016
ISSN: 1364-503X,1471-2962
DOI: 10.1098/rsta.2016.0148